Description

The DIALYSER 200ST NEPHRAL, also known as NEPHRAL ST 200, is a specialized high-flux dialyzer crafted by Gambro for advanced renal replacement therapy. It is designed for use in hemodialysis (HD), hemodiafiltration (HDF), and hemofiltration (HF), primarily targeting the effective removal of uremic toxins and inflammatory mediators through diffusion and adsorption.

Membrane Technology

• Type: AN 69 ST membrane, composed of acrylonitrile and sodium methallyl sulfonate copolymer.
• Surface Treatment: Polyethyleneimine, enhancing biocompatibility and adsorption properties.
• Heparin Adsorptive Hydrogel: Allows for reduced heparin use, minimizing systemic heparinization risks.

Specifications

• Surface Area: 1.05 m²
• Ultrafiltration Coefficient: 33 mL/h/mmHg
• Priming Volume: 64 mL
• Blood Pressure Drop: 87 mmHg
• Maximum Transmembrane Pressure: 450 mmHg
• Minimum Blood Flow Rate: 150 mL/min
• Recommended Ultrafiltration Flow Rate: 2 L/h during priming
• Rinseback Volume: 300 mL
• Weight: 160 g

Construction

• Housing Material: Polycarbonate
• Potting Material: Polyurethane
• Sterilization Method: Gamma ray (wet)

Clinical Benefits

The dialyzer's high biocompatibility makes it suitable for patients with hypersensitivity to conventional membranes. It effectively adsorbs uremic toxins and inflammatory mediators such as β2 microglobulin, TNF-α, IL-6, and IL-8. This design is intended to minimize complications associated with systemic heparinization.

Contraindications

The DIALYSER 200ST NEPHRAL is contraindicated for patients with a known allergy to heparin or those with Heparin-Induced Thrombocytopenia (HIT) Syndrome type II.

Intended Use

This dialyzer is intended for patients with chronic renal failure requiring HD, HDF, or HF, offering a reliable solution for effective and safe dialysis treatment.